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Journal Article 2

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2022 1

2012 1

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liposomes 2

boron neutron capture therapy 1

encapsulation efficiency 1

folate-targeted 1

microfluidics 1

phase separation 1

ternary droplets 1

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Microfluidic production of liposomes through liquid–liquid phase separation in ternary droplets

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 6, Pages 1017-1022 doi: 10.1007/s11705-021-2118-y

Abstract: Liposomes, the self-assembled phospholipid vesicles, have been extensively used in various fields suchHowever, current microfluidic routes to liposomes mostly rely on water-in-oil-in-water double emulsionHere we present a simple microfluidic approach to preparing monodisperse liposomes from oil-in-waterresultant water-in-oil-in-water droplets underwent a dewetting transition to form separated monodisperse liposomesmicrofluidic devices and tedious manipulation, and provides a new platform for controllable preparation of liposomes

Keywords： microfluidics liposomes ternary droplets phase separation

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Studies on preparation of folate-targeted boron liposomes as potential delivery agents for neutron capture

Wang Zhihui,Qin Linxue,Liu Dong

Strategic Study of CAE 2012, Volume 14, Issue 8, Pages 78-81

Abstract:

To prepare folate-targeted liposomes with high encapsulation efficiencyThe double emulsion method is used to prepare liposomes.The combination of thin film hydration and ultrasonic dispersion method is used to prepare liposomesThe optimal conditions for preparing BBA liposomes are as follows: the mass ratio of cholesterol andfolate-targeted liposomes is feasible and the method of quality control is simple and high accuracy.

Keywords： boron neutron capture therapy liposomes folate-targeted encapsulation efficiency